Interleukin-4 and interleukin-13 potentiate interleukin-1 induced secretion of interleukin-6 in human osteoblast-like cells
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چکیده
منابع مشابه
Wrestlers’ immune cells produce higher interleukin-6 and lower interleukin-12 and interleukin-13 in response toin vitro mitogen activation
Objective(s):Although recent investigations have shown chronic inflammation and inflammation-associated diseases might be ameliorated by exercise; little is known about the relation between exercise training with anti/pro-inflammatory cytokines. Materials and Methods: This cross sectional study was conducted to compare interleukin-4 (IL-4), IL-6, IL-10, IL-12, IL-13, interferon gamma (IFN-γ) le...
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a:4:{s:10:"Background";s:504:"While the etiology of PCOS has continued to remain a mystery, there can be found some evidence in support of the presence of chronic low-grade inflammation in women with this syndrome. One of the most significant manifestations of chronic inflammation is Pro-inflammatory cytokines. Therefore, the aim of this prospective study was to investigate the pattern of proinfla...
متن کاملEffects of cortisol on the expression of interleukin-6 and interleukin-1 beta in human osteoblast-like cells.
High levels of glucocorticoids are believed to alter bone remodeling by decreasing bone formation and increasing bone resorption. It has been suggested that different cytokines, like interleukin-6 (IL-6) and interleukin-1 (IL-1), are involved in bone resorption by activating immature osteoclasts, and some studies indicate that IL-6 promotes bone formation by a mitogenic effect on osteoblasts. T...
متن کاملInterleukin-4 and interleukin-13 increase NADPH oxidase 1-related proliferation of human colon cancer cells
Human colon cancers express higher levels of NADPH oxidase 1 [NOX1] than adjacent normal epithelium. It has been suggested that reactive oxygen species [ROS] derived from NOX1 contribute to DNA damage and neoplastic transformation in the colon, particularly during chronic inflammatory stress. However, the mechanism(s) underlying increased NOX1 expression in malignant tumors or chronic inflammat...
متن کاملRelationship of Interleukin-4 and Interleukin-6 with Pigmentation Disorders in Sardasht Sulfur Mustard-Exposed Veterans 20 Years after Exposure
Aims: Pigmentation disorders are one of the main skin problems due to mustard gas exposure in chemically-injured veterans. The aim of this study as part of the Sardasht cohort study was to investigate the association between IL-6 and IL-4 and pigment disorders in chemically-injured veterans exposed to mustard gas. Materials & Methods: In this study, 500 subjects including 372 people expose...
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ژورنال
عنوان ژورنال: Journal of Orthopaedic Research
سال: 2004
ISSN: 0736-0266,1554-527X
DOI: 10.1016/j.orthres.2004.02.008